Science

August 2026

A Digital Behavioral Health Game for Adolescent Mental Health A Prespecified Secondary Analysis of a Randomized Clinical Trial

This paper presents findings from a randomized clinical trial showing that our PlaySmart digital health game helped reduce depressive symptoms in adolescents over 12 months. More >

January 2026

A videogame for perceived risk of harm from opioid misuse in adolescents: a randomized controlled trial

This paper presents early results of the Randomized Controlled Trial (RCT) for PlaySmart, a serious game targeting perceived risk of harm from opioid misuse in adolescents. More >

April 2025

Adolescent extracurricular activities and perception of risk of harm from binge drinking

This paper examines the association between participation in extracurricular activities and perception of risk of harm from binge drinking among adolescents. More >

February 2024

Systematic Review of Interventions with Some School Involvement for School Refusal in High School–Age Adolescents

This paper describes a systematic review to determine potential aspects of interventions, in school settings or involving a school-based component, that are successful in addressing school refusal among high school–age adolescents. More >

November 2023

A Serious Video Game Targeting HIV Testing and Counseling: A Randomized Controlled Trial

This paper describes the results of the Randomized Controlled Trial (RCT) for PlayTest!, a serious game targeting HIV testing and counseling. More >

November 2023

A Video Game Intervention to Prevent Opioid Misuse Among Older Adolescents: Development and Preimplementation Study

This paper describes the formative work done to develop our PlaySmart digital intervention, targeting mental health and opioid misuse in older adolescents. More >

September 2023

A digital health game to prevent opioid misuse and promote mental health in adolescents in school-based health settings: Protocol for the PlaySmart game randomized controlled trial

This paper outlines the protocol used in the Randomized Controlled Trial (RCT) evaluating our newest serious game, PlaySmart, in school-based health settings across Connecticut. More >